Descripción de la oferta
Organisation/Company Josep Carreras Leukaemia Research Institute (IJC) Research Field Medical sciences » Cancer research Researcher Profile Recognised Researcher (R2) Positions PhD Positions Application Deadline 22 Jul 2026 - 23:59 (Europe/Madrid) Country Spain Type of Contract Temporary Job Status Full-time Hours Per Week 39 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No
Offer Description
The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.
The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII).
The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services. The IJC has six locations integrated into reference hospitals: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.
We are looking for a Postdoctoral Researcher for the Chromatin biology laboratory led by Dr. Alejandro Vaquero.
Responsibilities and Qualifications
RESEARCH DESCRIPTION
The Chromatin Biology Laboratory, led by Alex Vaquero, is internationally recognized for its expertise in studying cellular response mechanisms under stress conditions. The group's main objective is to define the role of the Sirtuin family of enzymes in regulating genome stability and epigenetics in response to stress, and to understand their impact on cancer, senescence, and aging.
MAIN RESPONSIBILITIES
The successful candidate will explore the molecular and epigenetic mechanisms controlling the SIRT7/PAX5 interplay in B-cell differentiation and B-Acute Lymphoblastic Leukemia (B-ALL). The project takes a multidisciplinary approach, combining state-of-the-art molecular and cellular biology techniques with genomics, proteomics, metabolomics in mouse models and patient-derived leukemia models.
PhD in Biology, Biomedicine, Medicine, or a related discipline.
Strong interest in cancer biology, particularly the molecular and cellular mechanisms underlying stress response, hematological malignancies and immune regulation.
Demonstrated experience working with mouse models (essential), preferably in the context of leukemia and/or sirtuin biology.
Strong expertise in molecular and cellular biology techniques, including protein biochemistry, immunofluorescence, and flow cytometry (FACS), as well as experience with proteomic and genomic approaches (essential).
Previous experience in the study of stress response pathways and/or sirtuin biology is highly desirable.
Excellent communication, organizational, and teamwork skills.
Excellent written and spoken English.
Languages ENGLISH Level Excellent
Research Field Medical sciences » Cancer research
Internal Application form(s) needed
Benefits
3-year full-time postdoctoral contract, with the possibility of a one-year extension following a positive evaluation.
Highly competitive salary
An exciting and innovative multidisciplinary research project with strong potential to advance the treatment of B-cell acute lymphoblastic leukemia.
Incorporation in a well-established, multinational, dynamic and highly motivated team
The stimulating environment of the Barcelona metropolitan area.
The project will also involve collaboration with world leaders in clinical and pre-clinical study of B-ALL and drug discovery
Working in the outstanding multidisciplinary research environment of the Josep Carreras Leukaemia Research Institute.
Deadline
Please submit your application by July 22nd, 2026.
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